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HomeMental HealthFacet Results of Trazodone to Be Conscious of — Talkspace

Facet Results of Trazodone to Be Conscious of — Talkspace

Revealed on: 23 Might 2023

Side Effects of Trazodone to Be Aware of

Trazodone is an antidepressant medicine that’s sometimes prescribed to deal with depressive dysfunction and nervousness dysfunction and is used off-label for insomnia sleep problem. Trazodone works by altering serotonin ranges within the mind to enhance temper and sleep high quality. Whereas Tradozone use could be useful, there are widespread uncomfortable side effects and dangers to grasp and contemplate like with each medicine.

Understanding the uncomfortable side effects of Trazodone medication is crucial in case you’re contemplating taking this drug to alter your serotonin ranges — maintain studying to be taught extra. We’re overlaying every widespread facet impact, extreme however uncommon results to pay attention to, and how one can handle any antagonistic results you would possibly expertise after you begin taking this drug.   

Widespread Facet Results of Trazodone

Essentially the most distinguished Trazodone facet impact is drowsiness. In reality, the drug is usually used off-label to deal with insomnia. Different widespread uncomfortable side effects of Trazodone can embody:

  • Nausea
  • Vomiting
  • Dry mouth 
  • Throat irritation
  • Headache
  • Belly ache
  • Constipation
  • Low blood strain
  • Itchy eyes
  • Disorientation
  • Blurred imaginative and prescient
  • Coordination points
  • Fainting

Much less Widespread Facet Results of Trazodone

Weight achieve 

Does Trazodone trigger weight achieve? Gaining weight isn’t skilled when taking Trazodone medication. Medical trials urged that simply 1% of individuals would possibly achieve weight after taking it. Nonetheless, some later analysis exhibits each weight achieve and loss are doable. 


Incontinence is one other uncommon facet impact of excessive doses of Trazodone. Analysis suggests that individuals with urinary incontinence ought to severely contemplate this and maybe seek the advice of with a healthcare supplier earlier than taking Trazodone. 

Sexual dysfunction

In response to research, an estimated 1.5% of individuals taking Trazodone can have decreased intercourse need as a result of drug. Most individuals see a return of sexual need and genital sensitivity in time, although. 

Psychiatry and Prescriptions On-line

Obtain an analysis and prescription for psychological well being medicine (if wanted) from a psychiatry-trained medical supplier.

Critical Facet Results of Trazodone

Critical uncomfortable side effects from taking Trazodone embody suicidal ideas, worsening signs of melancholy, and decreased immune system effectivity. 

“There are a few uncomfortable side effects of Trazodone that we have to watch. The primary one is an irregular coronary heart rhythm, too quick or too sluggish. It might probably additionally lower the immune system’s effectivity, resulting in extra colds and infections. Bowel motion and urination irregularities can be trigger for concern. Unexplained bruising, complications, aches and pains, confusion, nervousness, fainting, coordination points, and blurred imaginative and prescient that decide up in frequency must be monitored.”

– Talkspace therapist Meaghan Rice, PsyD, LPC

Different reactions can happen because of Trazodone use, together with: 

  • Seizures 
  • Likelihood in coronary heart fee (quickening or slowing irregular heartbeat)
  • Modifications in habits, reminiscent of aggression or agitation
  • Hallucinations
  • Issue respiration

In the event you see any of those indicators affecting psychological well being reminiscent of suicidal ideas whereas on Trazodone, contact your physician instantly.  

Do Trazodone Facet Results Go Away?

The excellent news is that the majority of Trazodone’s uncomfortable side effects will resolve as your physique adjusts to having the drug in your system. Nonetheless, if any widespread facet impact persists or worsens, it’s best to ask your physician or healthcare supplier about altering your dosage or switching medicines altogether.

How lengthy do Trazodone uncomfortable side effects final?

Whereas most individuals discover antagonistic uncomfortable side effects start to subside in time, some could expertise them for prolonged durations and wish to discuss to their physician. 

The way to Handle Trazodone Facet Results

In the event you’re experiencing any disagreeable uncomfortable side effects associated to Trazodone, your physician can provide you concepts on how one can handle every antagonistic facet impact. 

For instance, easy methods to fight Trazodone uncomfortable side effects embody:

  • Monitoring your signs
  • Adjusting dosage quantity
  • Altering the time of day you’re taking it, or whether or not you’re taking it with meals or with out 
  • Making life-style modifications reminiscent of yoga, meditation, and exercising commonly  
  • Hydrating
  • Utilizing pure cures like ingesting ginger tea for nausea or taking probiotics for intestine well being

“Managing Trazodone uncomfortable side effects might embody ingesting further water, supporting a wholesome life-style, eliminating drug use — particularly NSAIDS and cigarette smoking — limiting or eliminating caffeine and/or alcohol, telling your physician something and every little thing you’re already taking, being cautious about dangerous actions that don’t enable room for the sedative impact of Trazodone, and ensuring your physician is aware of every little thing about earlier medical circumstances.”

– Talkspace therapist Meaghan Rice, PsyD, LPC

See If Trazodone Is Proper for You with Talkspace Psychiatry

Trazodone uncomfortable side effects can vary from gentle to extreme, and it’s vital for anybody contemplating this medicine to pay attention to them. Although most uncomfortable side effects are short-term, understanding that they could nonetheless happen is important. That is particularly vital in case you’re contemplating stopping medicine as there’s a likelihood of experiencing Trazodone withdrawal signs. 

In the event you’re wanting into whether or not Trazodone could also be an excellent match on your psychological well being wants, Talkspace on-line psychiatry companies supply personalised assessments with licensed professionals who will help decide if this or some other medicine may benefit you. Get assist  right now.


  1. DailyMed – Trazodone Hydrochloride Pill. U.S. Nationwide Library of Medication. Accessed March 10, 2023. 
  2. Gica S. Investigation of the impact of Trazodone on spontaneous and acetylcholine-induced bladder detrusor clean muscle contractions. Dusunen Adam:The Journal of Psychiatry and Neurological Sciences. 2022. doi:10.14744/dajpns.2022.00170.  Accessed March 10, 2023. 
  3. Trazodone hydrochloride – Drug Abstract. Trazodone Hydrochloride (trazodone hydrochloride) dose, indications, antagonistic results, interactions… from PDR.internet. https://www.pdr.internet/drug-summary/Trazodone-Hydrochloride-trazodone-hydrochloride-3033.1692. Accessed March 10, 2023. 

Talkspace articles are written by skilled psychological health-wellness contributors; they’re grounded in scientific analysis and evidence-based practices. Articles are extensively reviewed by our crew of scientific specialists (therapists and psychiatrists of varied specialties) to make sure content material is correct and on par with present trade requirements.

Our purpose at Talkspace is to offer essentially the most up-to-date, precious, and goal info on psychological health-related matters as a way to assist readers make knowledgeable choices.

Articles include trusted third-party sources which are both instantly linked to within the textual content or listed on the backside to take readers on to the supply.

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