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Salt substitute is a cheap intervention for stroke prevention and improved high quality of life

A salt substitute that accommodates much less sodium was a cheap intervention for prevention of stroke and improved high quality of life, in line with an evaluation printed within the journal Circulation.

A earlier examine discovered the substitute was efficient at stopping stroke and coronary heart assault, so these findings additional cement this intervention’s usefulness, in line with Darwin Labarthe, MD, PhD, MPH, professor of Preventive Medication within the Division of Epidemiology and a co-author of the examine.

As a result of hypertension is so extremely prevalent, and prices of its morbidity and mortality outcomes are so nice, a cost-saving intervention has large implications for nationwide well being expenditures.”

Darwin Labarthe, MD, PhD, MPH, Professor of Preventive Medication, Division of Epidemiology

Lowering salt consumption reduces blood stress, which is a major contributor to illness and dying from coronary heart assault or stroke. As many as one billion individuals around the globe have uncontrolled hypertension, Labarthe mentioned, and that quantity solely continues to develop.

Salt substitutes — on this examine, a salt made from a mixture of sodium chloride and potassium chloride — have been proven to scale back blood stress. A earlier examine of greater than 20,000 people in 600 villages in northwestern China discovered charges of stroke, main cardiovascular occasions and dying have been all decrease in contributors utilizing salt substitutes when in comparison with contributors utilizing common salt.

Within the present examine, investigators carried out a cost-effectiveness evaluation of the earlier examine, measuring well being outcomes in quality-adjusted life years (QALYs). Healthcare prices have been recognized from participant medical health insurance information and estimated utilizing figures from earlier research.

Over the almost five-year follow-up interval, changing common salt with salt substitute decreased the danger of stroke by 14 p.c. The salt substitute group had on common 0.054 extra QALYs per individual. The common annual prices have been decrease within the salt-substitute group: 1,538 Chinese language yuan (about $241) for the intervention group and 1,649 Chinese language yuan (about $259) for the management group.

This implies the intervention was dominant — a time period utilized in cost-effectiveness denoting higher outcomes at decrease price — for prevention of stroke. Sensitivity analyses carried out by the authors confirmed these conclusions held even when the value of salt substitutes was raised, solely shedding cost-effectiveness when the value was elevated to the very best market costs recognized in China.

“This presents highly effective ‘exhausting consequence’ proof lengthy demanded by sodium discount skeptics who did not see the worth of interventions that might decrease blood stress itself, regardless of it being an immense well being and public well being downside,” Labarthe mentioned.

This intervention holds promise, particularly in nations akin to China the place massive segments of the inhabitants devour home-prepared relatively than commercially with processed meals, in distinction to Western nations akin to the US, in line with Labarthe.

“Governments and well being methods would profit and would serve their beneficiaries by implementing salt substitution as an necessary means to scale back blood stress and threat of stroke,” Labarthe mentioned. “This can be impactful to the diploma that particular person conduct determines how a lot salt is consumed; will probably be much less so the place the processed or manufactured meals predominate, till the meals trade adopts using salt substitute in its merchandise.”


Journal reference:

Li, Okay-C., et al. (2022) Price-effectiveness of a Family Salt Substitution Intervention: Findings From 20,995 Contributors of the Salt Substitute and Stroke Research (SSaSS). Circulation. doi.org/10.1161/CIRCULATIONAHA.122.059573.


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